This study aims to develop a tool that can be used by health workers to help identify very sick children (including those with sepsis) as soon as they arrive in hospitals, especially in areas with scarcity of trained health workers, and has been approved by SERU. The PRST will be a mobile application on a tablet and a pulse oximeter that can attach to the tablet. The PRST will also include a dashboard, which is a website that will display the triage data to provide real-time monitoring for the health care providers, sitting in clinical/consultation rooms at the outpatient area, who manage the patients. This study will take place at two hospitals located within vicinity of Nairobi county (Mbagathi and Kiambu County Hospitals) in Kenya and Jinja Regional Hospital in Jinja, Uganda. The study will employ study nurses and study assistants, supervised by the hospital leadership, to recruit participants, and perform study procedures including obtained informed consent which is required before participants are enrolled. The study will enroll 4000 patients at each hospital during a 16 months study duration and is planned to commence in December 2020.